Medical Research Council Research Fellow: 1979-1982.
Unit for Cancer Research, University of Leeds, Leeds, U.K.

​

Statistical Advisor: 1980-1981.
Yorkshire Urological Group and Gastrointestinal Group, St James University Hospital, Leeds,

​

Research Scientist Inserm (Chargé de Recherches): 1982-1986.
Unité de Recherches Statistiques, Villejuif, France.

​

Associate Professor of Biostatistics: 1986-1989
Department of Biostatistics, University of Washington, Seattle, U.S.A.

​

Research Scientist: 1986-1989.
Fred Hutchinson Cancer Research Center, Seattle, U.S.A.

​

Senior Research Scientist Inserm (Directeur de recherches): 1990-1992.
Département de Biostatistiques et de l'Informatique Médicale, Hôpital Saint Louis, Paris .

​

Full Professor of Mathematics with tenure: 1992-2002.
Department of Mathematics, University of California at San Diego, California, U.S.A.

​

Director: 1993 - 1996.
Laboratory of Mathematics and Statistics, University of California at San Diego, La Jolla, California, U.S.A.

​

Full Member: 1994 - 2002.
Cancer Center, University of California at San Diego, La Jolla, California, U.S.A.

​

Visiting Professor of Biostatistics: 1999.
Department of Biostatistics, Harvard School of Public Health, Boston. U.S.A.

​

Senior Research Scientist Inserm (Directeur de Recherches): 2002 - 2004
Institut Curie, Paris, France.

Visiting Professor of Biostatistics: 2004.
Department of Biostatistics, Harvard School of Public Health, Boston. U.S.A.

​

Full Professor of Mathematics: 2006-2007.
Department of Mathematics, Lancaster University, Lancaster, U.K.

 

Full Professor of Biostatistics: 2007-2009
Department of Public Health Sciences, University of Virginia, U.S.A. ​

​

Professor of Mathematics. 2011 - present 

Laboratoire de Probabilités, Statistique et Modélisation, Université Paris Sorbonne.

 

 

Promotion of the discipline​

 

Like all of my colleagues I support the discipline of biostatistics by giving service to the

profession. I have acted as Associate Editor for the journals Biometrical Journal, Frontiers in Psychology and Revue de l'Institut Statistique de l'Universite de Paris.  I am currently Associate Editor for the journals, Statistics in Medicine and Statistics in Biopharmaceutical Research. I have been a constant reviewer for almost all of the major journals in our discipline and have also reviewed and continue to review many articles for medical journals such as Journal of the National Cancer Institute and  Journal of Clinical Oncology. I have provided expert advice, including serving as an expert witness, on many occasions. I am an active member of a number of independent data monitoring committees. I have worked with many of the leading pharmaceutical companies, including Pfizer, Roche, Aventis, Novartis, GlaxoSmithKline and many more consistently over the years. With my colleague, Alexia Iasonos from the Memorial Sloan-Kettering Cancer Center, New York, we founded a series of workshops on early phase trial design. These have taken place in many cities in the United States, Europe and Japan. The next meeting takes place in Los Angeles in 2019. The website address for this 6th symposium is https://www.eiseverywhere.com/workshop6